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Ethylene Oxide Introduction

Ethylene oxide, also known as ethylene oxide, is a colorless liquid at low temperatures with an aromatic ether smell. It has a boiling point of 10.8°C, an odor threshold of 760 mg/m~1064 mg/m, and a density of 1.52; ethylene oxide is flammable and easy to explode, its minimum combustion concentration is 3%. Ethylene oxide gas has strong permeability.

Ethylene oxide sterilization device is a key equipment for manufacturers of single-use sterile medical devices. There are special requirements for installation, operation, and use management.

Ethylene oxide is a broad-spectrum disinfectant that can kill various microorganisms at room temperature, including spores, tuberculosis, bacteria, viruses, and fungi.

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Ethylene Oxide Advantage

  • 1

    Can kill all microorganisms, including bacterial spores.

  • 2

    Can penetrate irregular objects and sterilize.

  • 3

    Sterilized items can be wrapped and encapsulated as a whole to maintain a sterile state before use.

  • 4

    Relatively speaking, EO does not corrode plastics, metals and rubbers, and will not make items yellow or become brittle.

  • 5

    Can be used for the sterilization of items that cannot be soaked with disinfectant, dry heat, pressure steam and other chemical gases.

EO Sterilization Application

  • Hard and soft endoscopes

    Arthroscopy, bronchoscopy, cystoscopy, gastroscopy, colonoscopy, mediastinoscopy, ophthalmoscope, otoscope, pharyngoscope and rectoscopy, prostatectomy, thoracoscopy, urethroscopy.

  • Medical equipment

    Electric drills, electric burners, electric knife pens, dental drills, microsurgical instruments, nerve stimulators, pressure gauges, surgical instruments, bone drills, needles, artificial joints.

  • Plastic products

    Airway intubation, dilator, endotracheal intubation gloves, pacemaker, heart valve, nebulizer, petri dish, syringe.

  • Rubber products

    Catheters, dilators, drainage tubes, endotracheal tubes, surgical gloves, sheets.

  • Cosmetics

    Catheters, dilators, drainage tubes, endotracheal tubes, surgical gloves, sheets.

  • Medical equipment

    Anesthesia equipment, artificial kidneys, diathermy equipment, wires, meter heads, heart-lung machines, breathing, treatment equipment, hemodialysis.

  • Other

    Books, toys, linear probes, probes, thermometers, sutures

EO Sterilization Program

  • The ethylene oxide sterilization procedure needs to include preheating, pre-humidification, vacuuming, injecting vaporized ethylene oxide to reach a predetermined concentration, maintaining the sterilization time, clearing the ethylene oxide gas in the sterilization cabinet, and analyzing to remove the ethylene oxide's residue in bacteria products.

  • Ethylene oxide can be sterilized with 100% pure ethylene oxide or a mixed gas of ethylene oxide and carbon dioxide. The use of Freon is prohibited.

  • The analysis can be continued in an ethylene oxide sterilizer, or it can be placed in a special fume hood, and natural ventilation should not be used. The repeatedly input air should be filtered with high efficiency, which can filter out more than 99.6% of particles ≥0.3um.

  • Ethylene oxide residue mainly refers to the ethylene oxide and its two by-products, chloroethanol ethane and ethylene glycol ethane, left in articles and packaging materials after ethylene oxide sterilization; exposure to excessive ethylene oxide Residues can cause burns and irritation to the patient. The amount of ethylene oxide residue is related to the materials of the sterilized articles, the parameters of the sterilization, the packaging materials and the size of the packaging, the loading capacity, and the analysis parameters. When the polyvinyl chloride catheter is at 60℃, it is analyzed for 8h; when it is 50℃, it is analyzed for 12h. Some materials can shorten the resolution time, such as metal and glass can be used immediately, and some materials need to extend the resolution time, such as a built-in pacemaker. Ethylene oxide emission: The first choice for ethylene oxide emission in hospitals, the installation requirements: There must be a special exhaust piping system, and the exhaust pipe material must be ethylene oxide and not permeable such as copper pipes. Within 7.6m from the exhaust port, there should be no flammable materials and building air intakes such as doors or windows; if the length of the vertical part of the exhaust pipe exceeds 3m, a water collector must be installed, and the exhaust pipe should not be dented Or the loop will cause water vapor to accumulate or freeze in winter, blocking the pipeline; the exhaust pipe should be led to the outside and reversed at the exit to prevent water vapor from staying on the pipe wall or causing the pipe wall to be blocked; a professional must be requested Installation engineer, and install it in accordance with the requirements of the ethylene oxide sterilizer manufacturer. If ethylene oxide is discharged into the water, the entire discharge system (pipes, sinks, etc.) must be sealed, otherwise a large amount of heated ethylene oxide will overflow from the water and pollute the surrounding working environment.

Sterilization Process